Smoking remains as a global public health concern for many decades. About 1.4 billion people smoke worldwide, which is expected to rise to more than 1.6 billion by 2025. Tobacco-attributable deaths were 5 million in 2008 globally, which are projected to reach 8.3 million by 2030. Despite the significant awareness regarding the prevention and control on smoking mediated health hazards in recent years, it still remains as a leading cause of preventable death. BRAC Research and Evaluation Division (RED) conducted a study to track the prevalence of smoking in Manikgonj and Joypurhat districts in 1989. Hence, the present cross-sectional survey was carried out to investigate the changes in prevalence of smoking and associated factors over time in the same areas. General assumption is that the prevalence of smoking and smokeless tobacco use is more common in the areas where tobacco cultivation is ongoing compared to where not. To check this assumption, Kushtia district which is well known as a tobacco cultivating area has been included to compare the smoking prevalence with non-cultivating places (Manikgonj and Joypurhat districts). Two set of semi-structured questionnaires were employed to collect household and individual information from all households of the selected villages (3,663 households). The findings revealed that the percentage of households with at least one smoker was reduced by almost one third (71.6% vs. 48.6%) which is statistically significant (p-value<0.001). Significant reduction was also observed in prevalence of smoking irrespective of all ages and sexes. The study findings also indicated improvement (p-value<0.001) in level of awareness regarding negative health consequences of smoking. Findings showed that about 19.5% of adult men and women (aged 15 years and above) in the study areas currently smoke tobacco whereas, 18.2% use smokeless tobacco. The differences in the prevalence of smoker and smokeless tobacco user in tobacco cultivating and non cultivating areas were not statistically significant.